Research

Oxygen is Essential for life:

Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines

"Per AHA Guidelines: Ventilation is recommended in respiratory-driven emergencies (e.g., drowning, opioid overdose, pediatrics, pregnancy) where hypoxia — not the heart — is the cause of arrest."

Survival in Out-of-Hospital Cardiac Arrest After Standard

"Survival higher with standard CPR than compressions-only."

Riva 2019

Willingness to perform bystander cardiopulmonary resuscitation

"Willingness to perform bystander CPR drops when rescue breaths are required."

Matsuyama 2020

Changes in virus-transmission habits during the COVID-19 pandemic

"Post-COVID, reluctance to perform mouth-to-mouth has increased."

Rebar 2022

Bag-Valve-Mask Ventilation and Survival From Out-of-Hospital Cardiac Arrest

"BVM ventilation improves survival — but is too complex for lay responders."

Idris 2023

Building the Clinical Foundation for PROcan

We’re actively publishing papers that identify the clinical need for PROcan and introduce the PROcan concept. Our multidisciplinary team—MDs, paramedics, academic clinicians, and engineers—is moving quickly toward testing and clinical validation studies. Interested in learning more or getting involved? Reach out now!

Supporting Evidence

  1. 2020 AHA Guidelines – Part 3: Adult Basic & Advanced Life Support. Circulation (Panchal et al., 2020). AHA Journals+1
  2. Survival After Standard vs Compression-Only CPR in OHCA. Circulation (Riva et al., 2019). AHA Journals
  3. Willingness to Perform Bystander CPR: A Scoping Review. Resuscitation Plus (Matsuyama et al., 2020). PubMed+1
  4. Bag-Valve-Mask Ventilation & Survival from OHCA: Multicenter Study. Circulation (Idris et al., 2023). AHA Journals+2PubMed+2
  5. Epidemiology & Outcome of Prehospital Respiratory Distress. Acad Emerg Med (Prekker et al., 2014). PubMed+2PMC+2
  6. Highlights of the 2020 AHA CPR/ECC Guidelines (summary PDF). cpr.heart.org
  7. AHA CPR/ECC Guidelines – Executive Summary (Part 1). Circulation (Merchant et al., 2020). AHA Journals
  8. AHA CPR/ECC Guidelines Hub (landing page). cpr.heart.org
  9. Compression-Only vs Standard CPR: Systematic Review & Meta-analysis. (Bielski et al., 2023). PMC
  10. Compression-Only vs Standard CPR: Nationwide Randomized Pilot (Sweden). (Riva et al., 2024). AHA Journals+1
  11. AHA Algorithm: Opioid-Associated Emergency (Healthcare Provider). (AHA PDF). cpr.heart.org
  12. AHA Algorithm: Opioid-Associated Emergency (Lay Responder). (AHA PDF). cpr.heart.org
  13. Barriers/Facilitators to Bystander CPR During Emergency Calls: Scoping Review. Resuscitation Plus (Aldridge et al., 2022). ScienceDirect
  14. Editorial/Clinical Summary of Riva 2019 (NEJM Journal Watch). (useful interpretation piece). JWatch
  15. Institutional pages for the BVM survival study (USW/Elsevier Pure). (supplementary link). UT Southwestern
  16. Institutional pages for the respiratory-distress study (Elsevier Pure). (supplementary link). Oregon Health & Science University